808118-40-3 roxadustat

Eiddo

Ymddangosiad oddi ar wyn neu solid gwyn
Pwynt toddi: 199-215 gradd
Berwi: 684.3 ± 55. 0 Gradd (wedi'i ragweld)
Dwysedd 1.389
Temp Storio. -20 gradd
hydoddedd hydawdd yn DMSO (hyd at o leiaf 25 mg/mL).
PKA2.46 ± 0. 10
 

Cais:

Mae Roxadustat yn atalydd ffactor hypoxia inducible y geg propyl hydroxylase (HIF-PHI) a dderbyniodd ei gymeradwyaeth fyd-eang gyntaf yn Tsieina ym mis Rhagfyr 2018 ar gyfer trin anemia a achosir gan CKD mewn cleifion sy'n ddibynnol ar ddialysis.

 

Cyfystyron:

RoxadustatCity name (optional, probably does not need a translation)

808118-40-3

Fg -4592

FG4592

Roxadustat (fg -4592)

N-[({4- hydroxy -1- methyl -7- phenoxy -3- isoquinolinyl) carbonyl] glycine

ASP 1517

2- [({4- hydroxy -1- methyl -7- phenoxyisoquinoline -3- carbonyl) amino] amino] asid asetig asid asetig

RoxadustatumCity name (optional, probably does not need a translation)

Asp -1517

Glycine, n-[({4- hydroxy -1- methyl -7- phenoxy -3- isoquinolinyl) carbonyl]-

(((4- hydroxy -1- methyl -7- phenoxyisoquinolin -3- yl) carbonyl) amino) amino) asid asetig

N-[({4- hydroxy -1- methyl -7- phenoxyisoquinolin -3- yl) carbonyl] glycine

(4- hydroxy -1- methyl -7- phenoxyisoquinoline -3- carbonyl) glycine

2- (4- hydroxy -1- methyl -7- phenoxyisoquinoline -3- carboxamido) asid asetig)

EvrenzoCity name (optional, probably does not need a translation)

2- [[{4- hydroxy -1- methyl -7- (phenoxy) isoquinoline -3- carbonyl] amino] amino] asid asetig asid asetig

Glycine, n-(({4- hydroxy -1- methyl -7- phenoxy -3- isoquinolinyl) carbonyl)-

 

Tagiau poblogaidd: 808118-40-3 roxadustat, China 808118-40-3 gwneuthurwyr roxadustat, cyflenwyr